HILIC is a particularly useful separation mode for polar organic compounds that are poorly retained by reversed phase. Retention of these polar compounds using reversed phase methods is often difficult because of co-elutions with the solvent front or elutions within the chromatographic region where ion suppression is the greatest.
HILIC HPLC/UHPLC columns draw and retain a water-enriched layer onto the surface of the silica which facilitates the interaction of polar compounds with the stationary phase for increased retention.
|Luna Omega SUGAR||Polyamide/amine phase for the separation of polar analytes such as polyols/sugars|
|Kinetex HILIC||Novel core-shell unbonded silica phase provides significant selectivity for retention and separation of polar compounds|
|Luna HILIC||Offers excellent MS sensitivity and selectivity for polar compounds|
|Luna NH2||Amine phase applicable to multiple modes of chromatography and classes of polar compounds|
|Luna Silica(2)||Ultra-pure, metal-free silica particle that offers great polar selectivity.
|bioZen Glycan||Higher order separations of released N-Glycans and biomarkers.|