Normal phase chromatography (NPC) is used to separate hydrophobic compounds and matrices that are retained too strongly by reversed phase and have minimal solubility in aqueous mobile phases. Normal phase stationary phases typically include polar functional groups that interact with analytes primarily via dipole-dipole and hydrogen bonding interactions.
Normal phase stationary phases typically include polar functional groups (silica, amino, and cyano) and interact with analytes primarily via dipole-dipole and hydrogen bonding interactions.
Brand | Description: |
---|---|
Luna Silica(2) | Recommended for L3 USP methods |
Luna CN | Recommended for L10 USP methods |
Luna NH2 | Recommended for L8 USP Method |
Kinetex HILIC | Core-Shell Unbonded Silica |