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Applications
USP Alosetron Tablet Assay Standard/Sample solution (0.0115 mg/mL) on Gemini 3 µm C18 75 x 4.6 mm using Agilent 1260 Binary UHPLC
26385
Separation Mode: Reversed Phase
Reversed Phase
USP
C18
HPLC
Serotonin Antagonists
Pharmaceutical/Biopharmaceutical
Pharmaceutical
Therapeutic / Clinical

USP Alosetron Tablet Assay Standard/Sample solution (0.0115 mg/mL) on Gemini 3 µm C18 75 x 4.6 mm using Agilent 1260 Binary UHPLC

Analytes
1Alosetron HCl
Compound Name
Lotronex
CID
60758
Molecular Formula
C17H19ClN4O
Molecular Weight
330
No. Hydrogen Bond Acceptors
2
No. Hydrogen Bond Donors
2
Details
Official Method: USP
LC Conditions (App ID: 26385)
Column:
Brand Name:
Part No:
Phase Name:
C18
Elution Type:
Isocratic
Mobile Phase:
A: 0.02 M monobasic sodium phosphate. Adjust with phosphoric acid to a pH of 3.0
B: Acetonitrile
Gradient Profile:
Step No.Time(min)%A%B
110 80 20
Flow Rate:
1 mL/min
Temperature:
25°C
System:
Agilent Technologies Agilent Technologies
Detection:
LC/UV (DAD, PDA) @ 220.0000000000 nm (nanometers)

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