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Comparison of Polymeric and Silica-Based Columns for Oligonucleotide Analysis by Ion-Pair Reversed Phase
In this application note we compare the 2.6 µm Biozen Oligo to a 5 µm PS-DVB of similar dimensions in the separation of a 2’-MOE Gapmer, there is a marked difference in chromatographic performance, with the Biozen Oligo providing performance gains and robustness, along with improved recovery from bio-inert hardware.
Comparison of Polymeric and Silica-Based Columns for Oligonucleotide Analysis by Ion-Pair Reversed Phase
In this application note we compare the 2.6 µm Biozen Oligo to a 5 µm PS-DVB of similar dimensions in the separation of a 2’-MOE Gapmer, there is a marked difference in chromatographic performance, with the Biozen Oligo providing performance gains and robustness, along with improved recovery from bio-inert hardware.
Document Type:
Technical Notes
Target Industries:
Techniques:
Brands:
Separation Modes:
Reversed Phase
Phases:
Phenomenex is a technology leader committed to developing novel analytical chemistry solutions that solve the separation and purification challenges of researchers worldwide
Phenomenex is a technology leader committed to developing novel analytical chemistry solutions that solve the separation and purification challenges of researchers worldwide