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Documents
EPA Method 533: PFAS in Drinking Water (TN-0141)
EPA Method 533 supports monitoring of applications that include the analysis of multiple short chain PFAS that cannot be measured by Method 537.1, by utilizing a weak anion exchange mechanism in the sample extraction and preparation, improving the recovery of the short chained PFAS that do not retain well in a strictly reversed phase mechanism. This technical brief outlines the solid phase extraction (SPE) and liquid chromatography (HPLC) parameters included in the isotope dilution anion exchange SPE liquid chromatography / tandem mass spectrometry (LC-MS/MS) procedure detailed in the EPA Method 533.

EPA Method 533: PFAS in Drinking Water (TN-0141)

EPA Method 533 supports monitoring of applications that include the analysis of multiple short chain PFAS that cannot be measured by Method 537.1, by utilizing a weak anion exchange mechanism in the sample extraction and preparation, improving the recovery of the short chained PFAS that do not retain well in a strictly reversed phase mechanism. This technical brief outlines the solid phase extraction (SPE) and liquid chromatography (HPLC) parameters included in the isotope dilution anion exchange SPE liquid chromatography / tandem mass spectrometry (LC-MS/MS) procedure detailed in the EPA Method 533.
Document Type:
Technical Notes
Separation Modes:
Reversed Phase, Solid Phase Extraction