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Alternative LC Stationary Phase for he Separation of Benzalkonium Chloride Homologs (C12, C14, and C16)
In this application note, we utilize an alternative stationary phase, Biphenyl, to achieve the desired separation. The Biphenyl phase offers a unique combination of potential interactions (pi-pi, hydrogen bonding, dipole-dipole, and hydrophobic), making it a logical choice for the retention and separation of the benzalkonium chlorides, which are quaternary amines containing a phenyl group and lengthy alkyl chain (C12, C14, and C16).
Alternative LC Stationary Phase for he Separation of Benzalkonium Chloride Homologs (C12, C14, and C16)
In this application note, we utilize an alternative stationary phase, Biphenyl, to achieve the desired separation. The Biphenyl phase offers a unique combination of potential interactions (pi-pi, hydrogen bonding, dipole-dipole, and hydrophobic), making it a logical choice for the retention and separation of the benzalkonium chlorides, which are quaternary amines containing a phenyl group and lengthy alkyl chain (C12, C14, and C16).