Documents
Compendial Methods: Determination of Impurities and Related Substances (TN-1069)
Recently, a newly developed Kinetex 2.6 µm core-shell chromatographic particle has been commercialized that offers the performance benefits of sub-2 µm fully-porous particles but at substantially lower operating pressures. To demonstrate the performance benefits of this new core-shell technology, a Kinetex 2.6 µm core-shell C18 column was compared with a fully porous 5 µm C18 column referenced in EP ([Ph. Eur.] European Pharmacopoeia) Monograph 0703 for Atenolol and related substances on a conventional HPLC instrument with an upper pressure limit of 400 bar
Compendial Methods: Determination of Impurities and Related Substances (TN-1069)
Recently, a newly developed Kinetex 2.6 µm core-shell chromatographic particle has been commercialized that offers the performance benefits of sub-2 µm fully-porous particles but at substantially lower operating pressures. To demonstrate the performance benefits of this new core-shell technology, a Kinetex 2.6 µm core-shell C18 column was compared with a fully porous 5 µm C18 column referenced in EP ([Ph. Eur.] European Pharmacopoeia) Monograph 0703 for Atenolol and related substances on a conventional HPLC instrument with an upper pressure limit of 400 bar
Document Type:
Technical Notes
Target Industries:
Techniques:
Brands:
Separation Modes:
Reversed Phase
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