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Development of a Multi-Step Purification Process for the Purification of Exenatide (TN-1203)
The work presented here demonstrates the development of a multistep purification process on a single stationary phase for the crude synthetic peptide mixture of Exenatide. The focus of this technical note is on the initial development work, including the screening of multiple conditions to evaluate which steps will produce material of suitable purity. The investigated parameters include eluent pH, buffer components, and organic solvent composition.
Development of a Multi-Step Purification Process for the Purification of Exenatide (TN-1203)
The work presented here demonstrates the development of a multistep purification process on a single stationary phase for the crude synthetic peptide mixture of Exenatide. The focus of this technical note is on the initial development work, including the screening of multiple conditions to evaluate which steps will produce material of suitable purity. The investigated parameters include eluent pH, buffer components, and organic solvent composition.
Document Type:
Technical Notes
Target Industries:
Techniques:
Brands:
Separation Modes:
Reversed Phase
Phases:
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