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Optimization of Mobile Phase Composition for the Analysis of Synthetic Oligonucleotides using a Clarity Oligo-XT Column (TN-1200)
Mobile phase composition for the analysis of three different synthetic oligonucleotides models (Bridged Nucleic Acid, Antisense RNA, and DNA phosphorothioate) was studied and optimized using a Clarity 2.6 μm Oligo-XT C18 column.
Optimization of Mobile Phase Composition for the Analysis of Synthetic Oligonucleotides using a Clarity Oligo-XT Column (TN-1200)
Mobile phase composition for the analysis of three different synthetic oligonucleotides models (Bridged Nucleic Acid, Antisense RNA, and DNA phosphorothioate) was studied and optimized using a Clarity 2.6 μm Oligo-XT C18 column.
Document Type:
Technical Notes
Target Industries:
Biopharmaceutical Analysis, Pharmaceutical
Techniques:
HPLC, HPLC Reversed Phase, Oligonucleotide Analysis
Brands:
Clarity
Separation Modes:
Reversed Phase
Phases:
Clarity Oligo-XT
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