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Extraction and Analysis of THC and Metabolites from Whole Blood and Urine by GC-MS (TN-2062)
In this technical note we demonstrate a high recovery method for ?(9)-tetrahydrocannabinol (THC) and its metabolites 11-hydroxy-?(9)-tetrahydrocannabinol (11-OH-THC) and 11-nor-9-carboxy-?(9)-tetrahydrocannabinol (THC-COOH). We offer sample prep methods for urine using Strata Screen-C and for whole blood on Strata XL-A, followed by GC-MS using the Zebron ZB-5PLUS GC column. In both cases we achieved good separation of analytes and high recovery for all compounds.

Extraction and Analysis of THC and Metabolites from Whole Blood and Urine by GC-MS (TN-2062)

In this technical note we demonstrate a high recovery method for ?(9)-tetrahydrocannabinol (THC) and its metabolites 11-hydroxy-?(9)-tetrahydrocannabinol (11-OH-THC) and 11-nor-9-carboxy-?(9)-tetrahydrocannabinol (THC-COOH). We offer sample prep methods for urine using Strata Screen-C and for whole blood on Strata XL-A, followed by GC-MS using the Zebron ZB-5PLUS GC column. In both cases we achieved good separation of analytes and high recovery for all compounds.
Document Type:
Technical Notes
Techniques:
Separation Modes:
Gas Chromatography