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A Comparison of Various Kinetex C18 Phases
When performing reversed phase LC separations, there is a natural tendency of method developers to first test a C18 phase, the most commonly used phase in LC applications. Today, there are many different C18 phases available to method developers so choosing a simple C18 column may prove to be more challenging than one had originally thought. This technical note explores the different C18 phases within the Kinetex core-shell family of HPLC/UHPLC columns to determine the differences as well as to provide a general guideline of how to select the most appropriate C18 phase for a variety of applications.
A Comparison of Various Kinetex C18 Phases
When performing reversed phase LC separations, there is a natural tendency of method developers to first test a C18 phase, the most commonly used phase in LC applications. Today, there are many different C18 phases available to method developers so choosing a simple C18 column may prove to be more challenging than one had originally thought. This technical note explores the different C18 phases within the Kinetex core-shell family of HPLC/UHPLC columns to determine the differences as well as to provide a general guideline of how to select the most appropriate C18 phase for a variety of applications.
Document Type:
Guide
Target Industries:
Techniques:
Brands:
Separation Modes:
Reversed Phase
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