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Acids, Neutrals and Bases Using Novum Simplified Liquid Extraction (SLE) (TN-0121)
We developed a SLE application for acids (THC-COOH), neutrals (barbiturates), and bases (Norbuprenorphine and Buprenorphine) from a urine matrix containing ß-glucuronidase followed by two LC-MS/MS methods using a Kinetex EVO C18 LC column and SCIEX API 4000 mass spec in negative mode electrospray ionization (ESI-) and a Kinetex Biphenyl LC column and SCIEX API 4000 mass spec in positive mode electrospray ionization (ESI+).
Acids, Neutrals and Bases Using Novum Simplified Liquid Extraction (SLE) (TN-0121)
We developed a SLE application for acids (THC-COOH), neutrals (barbiturates), and bases (Norbuprenorphine and Buprenorphine) from a urine matrix containing ß-glucuronidase followed by two LC-MS/MS methods using a Kinetex EVO C18 LC column and SCIEX API 4000 mass spec in negative mode electrospray ionization (ESI-) and a Kinetex Biphenyl LC column and SCIEX API 4000 mass spec in positive mode electrospray ionization (ESI+).
Document Type:
Technical Notes
Target Industries:
Techniques:
Separation Modes:
Reversed Phase, Supported Liquid Extraction
Phases:
Acids, Neutrals and Bases Using Novum Simplified Liquid Extraction (SLE) (TN-0121)
We developed a SLE application for acids (THC-COOH), neutrals (barbiturates), and bases (Norbuprenorphine and Buprenorphine) from a urine matrix containing ß-glucuronidase followed by two LC-MS/MS methods using a Kinetex EVO C18 LC column and SCIEX API 4000 mass spec in negative mode electrospray ionization (ESI-) and a Kinetex Biphenyl LC column and SCIEX API 4000 mass spec in positive mode electrospray ionization (ESI+).
| Target Industries: | Cannabis and Hemp, Clinical Research, Forensic Toxicology |
| Techniques: | Sample Preparation, Supported Liquid Extraction |
| Brands: | Kinetex, Novum |
| Separation Modes: | Reversed Phase, Supported Liquid Extraction |
| Phases: | Kinetex Biphenyl, Kinetex EVO C18 |
Phenomenex is a technology leader committed to developing novel analytical chemistry solutions that solve the separation and purification challenges of researchers worldwide.
Phenomenex is a technology leader committed to developing novel analytical chemistry solutions that solve the separation and purification challenges of researchers worldwide.