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mRNA Characterization, From 5' Cap to Poly (A): What IP-RP-MS Can Tell You
mRNA is a biotherapeutic modality used in vaccines and vaccine development. Robust analytical methods are crucial for quality decisions. The manufacturing process involves in vitro transcription, resulting in mRNA molecules over 1000 nucleotides with a 5� cap and a Poly(A) tail. Contaminants must be quantified for assessing mRNA purity. This webinar presents an LC-MS characterization method for 5� Cap, Open Reading Frame (ORF), and Poly(A) tail.

mRNA Characterization, From 5' Cap to Poly (A): What IP-RP-MS Can Tell You

mRNA is a biotherapeutic modality used in vaccines and vaccine development. Robust analytical methods are crucial for quality decisions. The manufacturing process involves in vitro transcription, resulting in mRNA molecules over 1000 nucleotides with a 5� cap and a Poly(A) tail. Contaminants must be quantified for assessing mRNA purity. This webinar presents an LC-MS characterization method for 5� Cap, Open Reading Frame (ORF), and Poly(A) tail.
Document Type:
Poster
Target Industries:
Brands:
Separation Modes:
Reversed Phase
Phases:
Products used in this document
00D-4791-AN
bioZen 1.7 µm Oligo, LC Column 100 X 2.1 mm, Ea
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