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LC-MS/MS Analysis of Immunosuppressants from Whole Blood (TN-1169)
In this current work, we present a rapid and effective method for the analysis of cyclosporine A, tacrolimus, sirolimus, and everolimus from whole blood that uses a simple protein precipitation step followed by direct injection onto a wide-pore core-shell HPLC column Aeris WIDEPORE 3.6 μm XB-C18). The method displays excellent accuracy and is sensitive down to the low μg/L (ng/mL) range.
LC-MS/MS Analysis of Immunosuppressants from Whole Blood (TN-1169)
In this current work, we present a rapid and effective method for the analysis of cyclosporine A, tacrolimus, sirolimus, and everolimus from whole blood that uses a simple protein precipitation step followed by direct injection onto a wide-pore core-shell HPLC column Aeris WIDEPORE 3.6 μm XB-C18). The method displays excellent accuracy and is sensitive down to the low μg/L (ng/mL) range.
Document Type:
Technical Notes
Target Industries:
Techniques:
Brands:
Separation Modes:
Reversed Phase, Solid Phase Extraction
Phases:
LC-MS/MS Analysis of Immunosuppressants from Whole Blood (TN-1169)
In this current work, we present a rapid and effective method for the analysis of cyclosporine A, tacrolimus, sirolimus, and everolimus from whole blood that uses a simple protein precipitation step followed by direct injection onto a wide-pore core-shell HPLC column Aeris WIDEPORE 3.6 μm XB-C18). The method displays excellent accuracy and is sensitive down to the low μg/L (ng/mL) range.
| Target Industries: | Biopharmaceutical Analysis, Clinical Research, Forensic Toxicology, Pharmaceutical |
| Techniques: | HPLC, HPLC Reversed Phase, Sample Preparation, Solid Phase Extraction |
| Brands: | Aeris HPLC Column, StrataX |
| Separation Modes: | Reversed Phase, Solid Phase Extraction |
| Phases: | Aeris Widepore XB-C18, Strata-X-CW |
Phenomenex is a technology leader committed to developing novel analytical chemistry solutions that solve the separation and purification challenges of researchers worldwide.
Phenomenex is a technology leader committed to developing novel analytical chemistry solutions that solve the separation and purification challenges of researchers worldwide.