Evaluation of Extraction Options for EPA Method 1633 (TN-0155)

EPA Method 1633 provides a standardized approach for measuring up to 40 PFAS in a diverse range of environmental matrices. This method demands a two-step sample prep approach that adds a clean-up step, but this has practical limitations, is labor intensive, and could interfere with lab workflow and sample throughput. To streamline this process, Strata PFAS cartridges were developed as a single cartridge stacked with Strata-X-AW and Strata GCB sorbents that function as a traditional SPE cartridge with a built-in polishing step to meet the method guidelines. This technical note presents a study to validate method performance for the broader compound list in EPA 1633 and demonstrate the same utility for both water and soil extracts when using Strata PFAS solid phase extraction cartridges for sample prep.