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Optimizing SEC Column Selection for Accurate Biologic Characterization
Accurate size-exclusion chromatography (SEC) relies on selecting the appropriate pore size to ensure precise molecular weight characterization across diverse biomolecules. This flyer highlights comparative data generated using Biozen dSEC columns with 90 Å, 200 Å, and 700 Å pore sizes, demonstrating broad molecular weight coverage from proteins to long DNA and RNA fragments. Results illustrate how optimized pore architectures enable consistent, high-resolution separations while maintaining excellent recovery and minimal secondary interactions. Together, the Biozen dSEC chemistries provide a unified, flexible platform for reliable characterization of biologics and nucleic acids across low- to high-molecular-weight ranges.
Optimizing SEC Column Selection for Accurate Biologic Characterization
Accurate size-exclusion chromatography (SEC) relies on selecting the appropriate pore size to ensure precise molecular weight characterization across diverse biomolecules. This flyer highlights comparative data generated using Biozen dSEC columns with 90 Å, 200 Å, and 700 Å pore sizes, demonstrating broad molecular weight coverage from proteins to long DNA and RNA fragments. Results illustrate how optimized pore architectures enable consistent, high-resolution separations while maintaining excellent recovery and minimal secondary interactions. Together, the Biozen dSEC chemistries provide a unified, flexible platform for reliable characterization of biologics and nucleic acids across low- to high-molecular-weight ranges.
Document Type:
Poster
Target Industries:
Techniques:
Brands:
Separation Modes:
Size Exclusion
Phases:
Optimizing SEC Column Selection for Accurate Biologic Characterization
Accurate size-exclusion chromatography (SEC) relies on selecting the appropriate pore size to ensure precise molecular weight characterization across diverse biomolecules. This flyer highlights comparative data generated using Biozen dSEC columns with 90 Å, 200 Å, and 700 Å pore sizes, demonstrating broad molecular weight coverage from proteins to long DNA and RNA fragments. Results illustrate how optimized pore architectures enable consistent, high-resolution separations while maintaining excellent recovery and minimal secondary interactions. Together, the Biozen dSEC chemistries provide a unified, flexible platform for reliable characterization of biologics and nucleic acids across low- to high-molecular-weight ranges.
| Target Industries: | Biopharmaceutical Analysis |
| Techniques: | HPLC, Gel Filtration Chromatography (GFC), HPLC-SEC |
| Brands: | Biozen LC |
| Separation Modes: | Size Exclusion |
| Phases: | Biozen dSEC-1, Biozen dSEC-7 |
Phenomenex is a technology leader committed to developing novel analytical chemistry solutions that solve the separation and purification challenges of researchers worldwide.
Phenomenex is a technology leader committed to developing novel analytical chemistry solutions that solve the separation and purification challenges of researchers worldwide.