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HPLC
Axia Preparative Chromatography Columns
Innovative Packing and Hardware Technology

Axia columns are packed in a single axial compression step. This eliminates any decompression or "relaxation" of the sorbent and solves common problems associated with conventional packing processes for preparative columns.
The Axia packing method is completely automated and monitored by multiple sensors which allow measurement and recording of all process parameters for every column.
The result is an improved, more repeatable packing process, that offers the following benefits for Prep chromatographers:
- Elimination of media collapse
- Long column lifetimes
- Efficiencies and peak symmetries on par with analytical separations

21.2mm
50 x 21.2
75 x 21.2
100 x 21.2
150 x 21.2
250 x 21.2

30mm
50 x 30
75 x 30
100 x 30
150 x 30
250 x 30

50mm
50 x 50
100 x 50
150 x 50
250 x 50
Reproducible Column-to-Column Efficiency
Average Efficiency (N) with Synergi 4 µm Hydro-RP 100 x 21.2 mm

Reproducible Column-to-Column Peak Asymmetry
Average Peak Asymmetry with Gemini 5 µm C18 50 x 21.2 mm

Axia is patented by Phenomenex. U.S. Patent No. 7,674,383
Technical Library
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Technical Notes
- Improving Preparative HPLC Column Lifetime
- Optimization of Preparative Production
- Purification of Optically Active Pharmaceutical Compounds using Axial Compressed Columns
- Impact of pH on Purity and Yield
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